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J. Infertil. Reprod.
Biol. Volume 7, Issue 1, 2019 |
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Dysgerminoma in a Case of Swyer Syndrome
Journal of Infertility and reproductive Biology, 2019,
Volume 7, Issue 1, Pages 1-3, | Full Text in
PDF
and
HTML (267 KB)| Bishista Bagchi, Sukanta Misra, Ashish Seal
1. Senior Resident of Department of Obstetrics and Gynaecology,Vivekananda Institute of Medical Sciences 2. Professor and Head of Department of Obstetrics and Gynaecology,Vivekananda Institute of Medical Sciences 3. Assistant Professor Consultant of Department of Obstetrics and Gynaecology,Vivekananda Institute of Medical Sciences Abstract: Swyer syndrome or pure 46XY gonadal dysgenesis is a condition in which the individuals are phenotypically female; classically present as sexually infantile phenotypic females with primary amenorrhoea. The purpose of reporting this case is that it is extremely rare and the importance of diagnosis of females with gonadal dysgenesis for appropriate and early management. We are reporting a case of Swyer syndrome at Vivekananda Institute of Medical Sciences, Kolkata. The treatment required multi-disciplinary approach in terms of prevention of malignancy and osteoporosis, induction of puberty, fertility, and psychological support. Laparoscopy and gonadectomy being the mode of management as and when required, has been done in this case. Early diagnosis and management is extremely necessary as there is a high incidence of gonadal malignancies and also to discuss about fertility options; being an important aspect of these patients.
Keywords:
Swyer syndrome, Gonadal dysgenesis, Laparoscopy, Gonadectomy
Hormonal Effect on Male Fertility and Stem Cell Survival
Journal of Infertility and reproductive Biology, 2019, Volume 7, Issue 1, Pages 4-7, | Full Text in PDF and HTML (267 KB)| Eswari Beeram
Research scholar, Department of Biochemistry, Sri Venkateswara University, Tirupathi- 517502, Andhrapradesh, India
Abstract: Hormonal protection against male infertility was unknown to most of the physicians. Hormonal protection through suppression was proven excellent for the stem cell survival in testis, where as in other tissues it remains obscure. The hormonal suppression of male infertility was done mainly using testicular harmones like FSH and testosterone, Whereas GH is mainly involved in neuroprotective effects and protection against ischaemia compared to male fertility. Substances like resveratrol, also protect male fertility by improving the sperm motility. Stem cell survival through hormonal suppression and protective effects of other compounds like resveratrol against sperm motility was proven to be useful to the mankind with respect to male infertility.
Keywords: FSH, LH, Testosterone, Harmonal suppression, Stem cells
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